eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | li-fraumeni syndrome |
| Comorbidity | C0001418|adenocarcinomas |
| Sentences | 1 |
| PubMedID- 25926079 | Development of novel therapies to battle lung cancer has been greatly aided by the emergence of genetically engineered mouse models (gemms) of lung cancer, such as the k-rasg12d;p53frt/frt non–small cell lung carcinoma (nsclc) model [3], where the compound effect of conditional mutations in the k-ras oncogene and the p53 tumor suppressor gene leads to development of adenocarcinomas in the mouse lung [4]. |
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